埃里西佩洛特里克斯 (Erysipelothrix rhusiopathiae) 细菌病的治疗方法是使用线索利德 (linezolid)
Alex Berman1, Samuel C O Opara2, Yun F Wang3
1Division of General Internal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
概括
人类罕见的感染Erysipelothrix rhusiopathiae bacteremia可能源于污染的环境,如污水. 这一案例突显了当传统疗法不适合时,口服linezolid的成功治疗.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
背景情况:
- 埃里西佩洛特里克斯 (Erysipelothrix rhusiopathiae) 是一种很少引起人类感染的动物性细菌,通常呈现为局部或全身性疾病.
- 人类E. rhusiopathiae感染通常与职业动物或动物产品暴露有关.
研究的目的:
- 报告一个罕见的Erysipelothrix rhusiopathiae bacteremia在人类中的病例.
- 讨论Erysipelothrix rhusiopathiae感染的治疗选择,特别是对β-lactam治疗的替代方案.
- 为突出口服线索利德在长期抗微生物治疗中的成功使用.
主要方法:
- 一个60岁的妇女患有Erysipelothrix rhusiopathiae bacteremia的病例报告.
- 临床表现与下水道排水损伤造成的腿部破伤有关.
- 治疗涉及最初的静脉注射青素,随后是口服线索利德的长期治疗.
主要成果:
- 患者出现了因污水暴露而引起的细菌病.
- 最初用静脉注射的青素治疗导致了临床改善.
- 通过使用linezolid成功完成了长时间的口服抗菌药物治疗.
结论:
- 埃里西佩洛特里克斯 (Erysipelothrix rhusiopathiae) 细菌病可能发生于非职业环境暴露,如受污染的水.
- 有限的数据存在于对beta-lactam治疗的替代品对于Erysipelothrix rhusiopathiae.
- 口服线索利德代表了长期治疗Erysipelothrix rhusiopathiae bacteremia的可行的替代方案.
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