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调查世卫组织用于评估抗微生物药物管理计划的AWaRe分类:单中心研究

Kazutaka Oda¹, Shinichiro Okamoto², Eisaku Iwanaga³

¹Department of Pharmacy, Kumamoto University Hospital, 1-1-1, Honjo, Chuo-ku, Kumamoto City, Kumamoto, 860-8556, Japan; Department of Infection Control, Kumamoto University Hospital, 1-1-1, Honjo, Chuo-ku, Kumamoto City, Kumamoto, 860-8556, Japan.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

|September 5, 2024

概括

由于非传染性抗生素使用增加,世界卫生组织的AWaRe分类可能无法有效评估抗菌药物管理计划. 这项研究强调了使用AWaRe来评估抗微生物药物管理方面的问题.

科学领域:

抗微生物药物管理管理
药理学药理学是指药理学的学科.
公共卫生公共卫生

背景情况:

世界卫生组织 (WHO) 提出了AWaRe (访问,观察,储备) 分类,以帮助抗菌药物管理计划 (ASP).
对非传染性疾病的抗生素使用增加可能会损害AWaRe在评估ASP中的有效性.
本研究评估了基于AWaRe分类的抗微生物药物使用模式,以确定ASP评估中的挑战.

研究的目的:

评估由AWaRe分类分类的抗微生物药物使用模式.
确定使用AWaRe分类来评估抗微生物管理计划 (ASP) 的具体挑战和局限性.

主要方法:

一项回顾性研究是在一家845张床位的医院进行的.
门诊抗菌药物使用数据是从医疗计费记录中提取的.
非传染性抗微生物的使用被定义为特定的药物和剂量,包括宏类药物,四环素,利法克西敏和硫甲醇-三甲 (ST).

主要成果:

在2015年1月至2024年3月期间,用于非传染性治疗的抗微生物药物显著增加,从25.3%增加到50.1% (金额/DDD),从46.3%增加到65.9% (处方日).
预防性ST药物的使用增加了2.4倍,而利法西明的使用增加了100倍以上.
除非感染性使用外",访问"类别的比率从31.9%增加到58% (金额/DDD) 和42%增加到78% (处方日).

结论:

AWaRe分类可能不适合在不同的医疗保健环境中评估和比较抗菌药物管理计划 (ASP).
非传染性抗生素使用的增加使使用当前的AWaRe框架对ASP的准确评估变得复杂.

关键词:

根据AWaRe的分类,AWaRe的分类是抗生素抗生素是一种抗生素.抗菌药物管理计划抗菌药物管理计划抗微生物药物是一种抗微生物药物.

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