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在先天性心脏病中的心律失常:全国范围的队列研究
Eva Havers-Borgersen1, Christian Jøns1, Jawad H Butt1
1Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
American heart journal
|September 5, 2024
概括
患有先天性心脏病 (CHD) 的成年人面临着明显更高的发病心律失常的风险,例如晚期心房阻塞和心房/. 这种增加的风险与死亡率更高的可能性有关.
科学领域:
- 心脏病学 心脏病学
- 成年人的先天性心脏病
- 电子生理学 电子生理学
背景情况:
- 由于存活率增加,患有先天性心脏病 (CHD) 的成年人群正在增长.
- 这种人口变化与心脏并发症的发病率上升有关,特别是心律失常.
- 在患有心脏病的成年人中,心律失常的长期风险仍未得到充分研究.
研究的目的:
- 为了研究患有先天性心脏病 (CHD) 的成年人心律不整的长期风险.
- 为了比较心律不整的发病率在CHD患者与一般人群.
- 为了确定与心律失常风险升高相关的特定心血管疾病亚型.
主要方法:
- 使用丹麦国家注册的观察队列研究.
- 包括1977年至2024年出生患有心血管疾病的所有丹麦患者.
- 随访直到心律失常的诊断,死亡,移民,或2024年3月,与年龄和性别匹配的对照.
主要成果:
- 45,820名心脏病患者与183,280名对照人群进行了比较.
- 慢性心脏病患者患心律失常的危险比率增加了16.4倍 (1.2对每1000年PY的0.1).
- 先进的心房阻塞和心房/心肌是最常见的;复杂的心脏病具有最高风险. 心律失常会使死亡风险增加6.9倍.
结论:
- 与普通人群相比,患有心脏病的成年人患心律失常的风险明显增加.
- 患有复杂形式的心脏病的人面临着特别高的发病心律失常的风险.
- 慢性心脏病患者的心律失常与死亡风险显著增加有关,这强调了需要改进管理策略的必要性.
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