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Updated: Jun 14, 2025

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues
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集成蛋白β类1由DNA甲基化调节,在心力衰竭患者中增加

Lauren Kerrigan1, Kevin Edgar1, Adam Russell-Hallinan1

  • 1Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.

ESC heart failure
|September 5, 2024
PubMed
概括

综合蛋白β类1 (ITGBL1) 在缺血性心脏病 (IHD) 的心力衰竭 (HF) 中受到上调和低甲基化. 这种基因主要存在于心脏纤维细胞中,驱动纤维细胞迁移,导致心脏纤维化.

关键词:
通过DNA甲基化.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.心脏衰竭是因为心脏衰竭.缺血性心肌病症 缺血性心肌病症单核RNA测序:心脏纤维细胞.

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