生物降解芯片含有Salvadora persica (miswak) 提取物在基索桑基中的临床疗效评估,作为治疗牙周炎的扩大和根平的辅助
Fouad H Al-Bayaty1, Azwin A Kamaruddin2, Mohd A Ismail3
1Faculty of Dentistry, Department of Periodontology, MAHSA University, Selangor, Malaysia.
含有Salvadora persica (miswak) 提取物的生物降解性牙周片在治疗牙周炎方面显著改善,为患者提供了有前途的辅助疗法.
科学领域:
- 牙周病学 牙周病学
- 生物材料科学 生物材料科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 牙周炎是一种普遍的炎症状况,影响牙的支结构.
- 目前的治疗方法通常涉及侵入性手术和全身药物.
- 对于局部和有效的牙周炎管理,需要新的药物输送系统.
研究的目的:
- 开发和评估可生物降解的牙周片的临床有效性.
- 评估含有Salvadora persica (miswak) 或基异硫酸 (BITC) 提取物的片,用于牙周炎的治疗.
- 为了比较这些芯片的疗效与对照和普通酸盐芯片.
主要方法:
- 进行了一项临床试验,涉及12名患者和240名牙周口袋 (≥5毫米).
- 参与者接受了缩放和根平整,随后进行了芯片应用 (对照组,普通奇托桑,S.persica或BITC).
- 临床参数包括斑块指数,探针出血,口袋深度和临床附着水平在基线和60天后被记录下来.
主要成果:
- 所有治疗组都在斑块指数,探针出血和口袋深度减少方面显著改善 (P <0.05).
- 与对照组和其他组相比,Salvadora persica芯片组在临床依恋水平上表现出明显更高的改善 (P <0.001).
结论:
- 含有Salvadora persica提取物的生物降解性牙周片作为牙周炎的辅助治疗有效.
- 这些芯片为牙周炎管理提供了局部和潜在的更有效的治疗选择.
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