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开发适用于个性化化品的奶油基

Magdalena Bîrsan^1,2, Ana Caterina Cristofor³, Cristina Tuchiluş⁴

¹Medicine and Pharmacy Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania.

Medicine and pharmacy reports

|September 5, 2024

概括

开发了个性化化品奶油基,并对各种制备方法的稳定性进行了测试. Euxyl® PE 9010在保存方面被证明是有效的,为定制产品确定了特定的配方.

科学领域:

化品科学化品科学
皮肤病学皮肤病学
配方化学配方化学是什么

背景情况:

对个性化化品和个性化皮肤制剂的需求日益增加.
需要稳定和有效的奶油基来定制配方.

研究的目的:

开发和评估用于个性化化和皮肤病应用的乳化基.
为了评估使用不同的同质化方法制备的奶油基的物理稳定性和质感.
为了确定开发的奶油基的最佳防腐剂.

主要方法:

使用经典,自动和半自动方法制备24种乳化基.
对基的物理稳定性和纹理参数的评估.
防腐剂 (NipaEster,Cosgard,Euxyl® PE 9010) 的抗菌有效性测试针对金黄色葡萄球菌,Pseudomonas aeruginosa和白菌.

主要成果:

在所有制备方法中,有9个奶油基表现出稳定性.
Euxyl® PE 9010被确定为一种有效的防腐剂.
根据制备方法观察到相同配方的纹理参数存在显著差异.

结论:

配方F1 (甲基葡萄糖六基酸盐),F8 (乙基酸盐) 和F14 (乙基酸盐-20) 适用于定制产品的奶油基.
制备方法对最终的奶油基质感有很大的影响.
建议使用Euxyl® PE 9010来保存这些定制的奶油基.

关键词:

抗微生物药物是一种抗微生物药物.个性化化品个人化品质地分析,质地分析.

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