相关实验视频

Updated: Jul 29, 2026

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis

Published on: September 26, 2016

针对非创伤性骨髓缩的各种干预措施的有效性:对联和网络元分析

Shaoyang Zhai¹, Rui Wu¹, Jie Zhao¹

¹Orthopedic Injury College, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.

Frontiers in endocrinology

|September 5, 2024

概括

细胞疗法和非手术性体外冲击波疗法 (ESWT) 与药物治疗显示出骨头骨硬化 (ONFH) 的最佳结果. 与手术单独相比,将手术与细胞治疗结合起来也可以改善结果.

科学领域:

整形外科整形外科整形外科
再生医学是一种再生医学.
临床试验临床试验

背景情况:

股骨头骨死 (ONFH) 是一个重大的骨科挑战.
非创伤性ONFH需要有效的治疗策略.

研究的目的:

评估各种干预措施对非创伤性ONFH的有效性.
为指导ONFH管理中的临床决策.

主要方法:

随机对照试验 (RCT) 的系统审查和元分析.
搜索的主要数据库 (PubMed,Embase,Cochrane,Web of Science) 截至2023年2月.
使用Cochrane偏差风险工具评估研究质量;使用Stata 15.1.1分析数据.

主要成果:

与对照组相比,细胞治疗,注射药物,ESWT和ESWT与药物联合显著改善了VAS疼痛得分.
细胞疗法在部部评分 (HHS) 中表现出最高的有效率,其次是ESWT加药.
在骨移植加细胞治疗的手术核心减压和仅使用骨移植的核心减压之间,在WOMAC和Lequesne评分中没有发现显著差异.

结论:

细胞疗法和非手术ESWT (单独或与药物/细胞疗法结合) 对ONFH非常有效.
通过骨移植加上细胞治疗进行的手术核心减压优于单独使用骨移植进行的核心减压.
对于急性ONFH,建议使用注射药物的ESWT;ESWT适用于慢性病例.

关键词:

核心压缩减压 (CD) 的核心压缩减压.身体外冲击波疗法 (ESWT) 是一种疗法.免费的血管化骨头移植 (FVFG)进行元分析.多重钻探解压缩 (MDD) 方法腿部头部骨髓缩 (ONFH) 的情况血管化或非血管化骨移植手术/切除 (VGF)

更多相关视频

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Published on: April 12, 2022

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Published on: September 27, 2024

相关概念视频

Protein Networks

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...