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Updated: Jun 14, 2025

In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell Lines
08:50

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m6由TGF-β调节的A-依赖ITIH1作为肝细胞癌进展的标

Zhibin Liao1,2, Hongwei Zhang1,2, Furong Liu1,2

  • 1Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|September 5, 2024
PubMed
概括

转化生长因子β (TGF-β) 促进METTL3的N6-甲基氨酸 (m6A) 修饰,降低ITIH1的稳定性,并促进肝细胞癌 (HCC). ITIH1蛋白抑制了HCC的进展,并显示了治疗潜力.

关键词:
在 ITIH1 的基础上.在TGF-ββ.肝细胞癌是肝细胞癌.集成/FAK信号传输m6A 一个很好的.

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