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Updated: Jun 14, 2025

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
11:08

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli

Published on: December 9, 2017

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基因代码扩展和重编程的工程皮罗素系统

Daniel L Dunkelmann1,2, Jason W Chin1

  • 1Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, England, United Kingdom.

Chemical reviews
|September 5, 2024
PubMed
概括

解-tRNA合成酶 (PylRS) /tRNAPyl对已经彻底改变了遗传代码的扩展,使非正规氨基酸 (ncAAs) 在所有生命领域的结合成为可能. 这项技术促进了新的应用和创建多样化的生物分子.

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