化合物概况,抗氧化剂和Elaeagnus conferta Roxb.的细胞保护活性. 果子 果子 果子
Jun Lu1,2, Dingli Liu1,2, Jing Cheng3
1Hunan Key Laboratory of Forestry Edible Sources Safety and Processing, Central South University of Forestry and Technology, Changsha, 410004, China.
Chemistry & biodiversity
|September 5, 2024
概括
罗克斯果 (Elaeagnus conferta Roxb) 的果实富含类化合物,如二米里塞丁和酸. 这些提取物表现出强大的抗氧化和细胞保护性质,表明它们在食品工业中的使用.
科学领域:
- 植物化学 植物化学
- 细胞生物学 细胞生物学
- 食品科学 食品科学 食品科学
背景情况:
- 罗克斯果 (Elaeagnus conferta Roxb) 是来自中国西南地区的未充分利用的资源.
- 了解它们的植物化学成分和生物活性对于潜在的应用至关重要.
研究的目的:
- 为了分析E. conferta水果的性概况.
- 为了评估它们的抗氧化活性.
- 评估它们对人类静脉内皮细胞 (HUVEC) 的保护作用.
主要方法:
- 超声波辅助提取用于样品制备.
- 超高性能液体色谱-电喷离子联质谱法 (UPLC-ESI-MS/MS) 确定了化合物.
- 使用Trolox相当的抗氧化能力测定来测量抗氧化活性.
- 对H2O2受损的HUVEC进行了细胞活力测试.
主要成果:
- 确定了15种化合物,包括酸和黄酸,其中二米瑞,基酸和酸占主导地位.
- 提取物显示出显著的抗氧化活性 (2.2587.844μM Trolox/g).
- 提取物通过降低活性氧物种 (ROS),氨酸 (MDA) 和乳酸脱酶 (LDH) 来保护HUVECs免受H2O2诱导的损伤,同时提高超氧化脱酶 (SOD) 水平.
结论:
- E. conferta 果实是富含高容量的抗氧化剂的丰富来源.
- 这些水果对内皮细胞具有显著的保护作用.
- 因此,E.conferta可以作为食品工业的有价值的替代成分.
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