在接受心脏再同步治疗的患者中,右心室-肺动脉合
Alessandra Roccabruna1, Federico Fortuni2, Alberto Comuzzi1
1Electrophysiology and Cardiac Pacing, Division of Cardiology, Cardio-Thoracic Department, University Hospital of Verona, Verona, Italy.
The international journal of cardiovascular imaging
|September 5, 2024
概括
三环状平面缩外流 (TAPSE) 与肺动脉缩压 (PASP) 的比率不能预测心脏再同步治疗 (CRT) 的反应. 然而,这种比率是CRT接受者的死亡率的一个强有力的预测指标.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 心脏衰竭管理的管理
背景情况:
- 右心室-肺动脉 (RV-PA) 合对心脏功能至关重要.
- 三环状平面缩外流 (TAPSE) 与肺动脉缩压 (PASP) 的比率作为RV-PA合的非侵入性标志物.
- 在接受心脏再同步治疗 (CRT) 的患者中,评估RV-PA合是至关重要的.
研究的目的:
- 研究TAPSE/PASP比率与CRT响应之间的关联.
- 在接受CRT的患者中确定TAPSE/PASP比率的预后值.
- 评估CRT对RV-PA合器的影响.
主要方法:
- 在2016年至2020年期间接受CRT的229名患者的回顾性分析.
- 心声学被用于评估基线和1年随访时的RV-PA合 (TAPSE/PASP比率).
- 多变量考克斯回归分析确定了所有原因死亡的预测因素.
主要成果:
- 基线TAPSE/PASP比率与CRT反应没有显著相关.
- 基线TAPSE/PASP比率较低的患者的生存率明显降低.
- 在CRT响应者中,TAPSE/PASP比率显著增加,但在非响应者中没有显著增加.
- 低估计的淋巴膜过率也与增加全因死亡率有关.
结论:
- 基线TAPSE/PASP比率并不能预测CRT响应.
- 在CRT接受者中,TAPSE/PASP比率是所有原因和心血管死亡率的重要独立预测指标.
- 在CRT后TAPSE/PASP比率的变化可能表明响应者治疗的有效性.
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