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生物信息管道用于分析食品传播细菌生态和耐短阅读元基因组学的耐药性

Pierre Lemée¹, Arnaud Bridier²

¹Antibiotics, Biocides, Residues and Resistance (AB2R) Unit, Fougères Laboratory, French Agency for Food, Environmental and Occupational Health & Safety (ANSES), Fougères, France.

Methods in molecular biology (Clifton, N.J.)

|September 5, 2024

概括

下一代测序为食品安全提供了有价值的数据. 本研究介绍了一种生物信息学工作流程,用于分析细菌生态学和食品中抗体组概况的猎枪元基因组数据.

科学领域:

食品微生物学食品微生物学
生物信息学是一种生物信息学.
基因组学就是基因组学.

背景情况:

下一代测序 (NGS) 已经改变了食品安全,通过使广泛的数据生成用于病原体监测.
射门甲基因组学是对食品中的微生物群落进行详细分析的强大工具,包括分类学和功能性见解.

研究的目的:

提供详细的生物信息学工作流程,用于分析猎枪元基因组数据.
为了使细菌生态和抗体组合在食品样本的特征.

主要方法:

使用猎枪元基因组测序来从食品样本中获得短读数据.
实施数据分析的逐步生物信息学管道.

主要成果:

工作流允许对细菌群落进行深入的分类学分析.
对抗体组合的表征,识别抗生素耐药性基因.

结论:

这种生物信息工作流对于全面的食品安全管理至关重要.
快枪元基因组学为了解食品微生物生态系统和耐药性提供了必要的数据.

关键词:

抗微生物耐药性抗微生物耐药性生物信息工作流程的工作流程微生物生态学微生物生态学一把枪的元基因组学.

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