在患有喉喉功能障碍的患者中,巴罗反射敏感性 - - 压倒性阴道假设
S A Reza Nouraei1, Lachlan Ayres2, Stephen J Perring3
1The Clinical Informatics Researchers Unit, Southampton University, United Kingdom.
JAMA otolaryngology-- head & neck surgery
|September 5, 2024
概括
患有喉喉症状的患者表现出降低的巴罗反射灵敏度,这表明与食管胃症状患者相比,自主控制受损. 这突显了在气消化器功能障碍中潜在的自主过载.
科学领域:
- 自主神经系统生理学 自主神经系统生理学
- 心血管监管 监管心血管系统
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 自主神经系统 (ANS) 通过优先考虑功能来调节内部稳定.
- 目前尚不清楚气消化结功能障碍是否会压倒ANS控制并影响其他身体功能.
- 巴罗反射灵敏度是ANS血压调节能力的关键指标.
研究的目的:
- 为了比较患有主要是消化症状的患者和患有空气消化症状的患者之间的巴罗反射灵敏度.
- 为了研究喉喉功能障碍对自主控制的影响.
主要方法:
- 这是一项涉及成年人进行食道测量或鼻腔泛镜的横截面研究.
- 测量心率和血压以得出巴罗反射灵敏度和心率变化.
- 评估食道生理学使用高分辨率测量.
主要成果:
- 与患有喉喉症状的患者相比,患有喉喉症状的患者表现出明显较低的巴罗反射灵敏度和副交感心率变异性.
- 空气消化组的静止心率较高,平均动脉压较低.
- 较低的食道松与降低的巴罗反射灵敏度相关.
结论:
- 喉喉症状与巴罗反射敏感性降低有关,这表明阴道控制受损.
- "压倒的模糊假设"表明,在空气消化道的高监管要求可以耗尽自主资源.
- 测量巴罗反射灵敏度可能有助于表型化喉功能障碍,并通过整体自主健康方法改善患者护理.
相关概念视频
Hyperpnea and Hyperventilation
992
Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
992
Other Factors Affecting Respiration Centers
783
Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical...
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical...
783
Gross Anatomy of the Lungs
1.7K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
1.7K
Neural Regulation of Blood Pressure
2.7K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
2.7K
Physiology of Respiration II: Neurogenic Control of Respiration
586
The neurogenic control of respiration coordinates various neural networks and pathways to regulate breathing rate and depth, meeting the body's oxygen and carbon dioxide exchange requirements. This system adapts to physiological and environmental conditions, ensuring optimal breathing patterns.
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
Central Control
The brainstem is the primary site of central control, hosting respiratory centers:
586
Chemical Factors Affecting Respiration Centers
1.0K
Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated....
CO2 has a potent influence on respiration and is strictly regulated....
1.0K


