复发性缺血性中风患者的急性症状性:一个多中心研究
Miguel Leal Rato1,2, Miguel Schön1, Maria Paula Zafra3
1Serviço de Neurologia, Departamento de Neurociências e Saúde Mental, Hospital de Santa Maria, ULS Santa Maria, Lisbon, Portugal.
Epileptic disorders : international epilepsy journal with videotape
|September 5, 2024
概括
与首次中风患者相比,再发性中风患者在住院期间不会面临急性症状发作的更高风险. 这项研究发现了类似的发作率,表明中风复发不会独立增加发作风险.
科学领域:
- 神经学 神经学
- 脑卒中医学 脑卒中医学
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 由于神经系统的变化,发作在中风后很常见.
- 在第一年内,中风复发会影响高达10%的患者.
- 了解复发性中风中的发作风险对于患者管理至关重要.
研究的目的:
- 确定患有复发性中风的患者急性症状性发作的风险.
- 为了比较第一次和复发性中风事件之间的发病率.
- 为了确定中脑动脉中风 (MCA) 发作的预测因素.
主要方法:
- 在5年内对缺血性中风患者的回顾性队列研究.
- 包括来自两个国际中心的患者进行验证.
- 排除了先前被诊断为的患者.
- 后勤回归用于识别MCA中风中的发作预测因素.
主要成果:
- 在复发 (5.1%) 和首次中风 (4.5%) 患者中,发作风险没有显著差异.
- 急性症状性发作风险也相当于 (5.0%对4.1%).
- 第一次MCA中风中的预测因素 (年龄,性别,出血) 在复发性中风中没有显著意义.
结论:
- 以前的中风史与住院期间发作风险增加无关.
- 需要进一步进行大规模的前性研究,并进行电生理学评估.
- 脑卒中复发似乎没有提高急性发作风险.
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