绝经后骨对间歇步行训练的反应增加取决于基线骨矿物质密度
Rizka Nugraheni Martyanti1, Mayuko Morikawa1,2,3,4, Masaaki Hanaoka4,5
1Departments of Sports Medical Sciences, Shinshu University Graduate School of Medicine, Nagano, Japan.
PloS one
|September 5, 2024
概括
间歇步行训练 (IWT) 对绝经后妇女有好处.
科学领域:
- 运动生理学 运动生理学
- 骨健康 骨健康 骨健康
- 老年学是一门学科.
背景情况:
- 骨质疏松症是绝经后妇女的一个重大问题.
- 绝经后,骨矿物质密度 (BMD) 自然会下降.
- 间歇步行训练 (IWT) 是对骨健康的潜在干预措施.
研究的目的:
- 调查基线骨矿物质密度 (BMD) 是否影响绝经后妇女间歇步行训练 (IWT) 的有效性.
- 为了确定基线BMD与IWT后的BMD变化之间的关系.
主要方法:
- 234名绝经后妇女 (64±5岁) 没有服用骨质疏松症药物参加了为期5个月的内输液治疗计划.
- IWT涉及交替快速 (≥70%的峰值有氧能力) 和缓慢 (≈40%) 每步3分钟,每天≥5次,每周≥4天.
- 在干预前后使用双能X射线吸收计 (DXA) 测量腰椎,大腿和全部的骨矿物质密度 (BMD).
主要成果:
- 基线BMD是所有测量骨部位的BMD增加的重要决定因素.
- 在IWT的反应中,BMD的增加在具有较低基线BMD的女性中更大.
- 基线 BMD 较低的女性显示显著增加 (LS:1.8%,FN:1.0%),而基线 BMD 较高的女性显示没有显著变化.
结论:
- 间歇步行训练 (IWT) 是一种安全有效的干预措施,用于改善绝经后妇女的骨矿物质密度 (BMD).
- 在基线较低的BMD患者中,IWT对BMD的积极影响更为明显.
- IWT为绝经后妇女的骨健康管理提供了一个有希望的,低副作用的策略.
相关概念视频
Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
Bone Remodeling
38.2K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.2K


