预期记忆的抱怨与多发性硬化症患者的客观表现有关
Daija A Jackson1, Aaron P Turner2, Sarah A Raskin3
1The Chicago School, Washington, DC; Department of Behavioral Health, Brooke Army Medical Center, San Antonio, TX.
Archives of physical medicine and rehabilitation
|September 5, 2024
概括
多发性硬化症 (PwMS) 患者的客观前性记忆 (PM) 性能与他们自我报告的记忆能力有关. 这一发现突显了感知赤字问卷-前性记忆 (PDQ-PM) 在PwMS中评估PM的实用性.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 临床神经学 临床神经学
背景情况:
- 预期记忆 (PM) 对日常运作至关重要.
- 多发性硬化症 (MS) 可以显著影响认知能力,包括PM.
- 了解MS中主观和客观PM之间的关系对于有效管理至关重要.
研究的目的:
- 研究多发性硬化症 (PwMS) 患者客观和主观前性记忆之间的关联.
- 为了确定客观的PM性能是否与PwMS内存的自我感知相一致.
- 探索影响该人口对PM主观评估的因素.
主要方法:
- 一项涉及112名PwMS的横截面队列研究的二次分析.
- 目标PM使用意向记忆测试 (MIST) 进行评估.
- 用感知缺陷问卷-前性记忆 (PDQ-PM) 测量主观的PM.
- 多变量模型考虑了人口统计,身体残疾,回顾性记忆,抑郁和疲劳.
主要成果:
- 在PwMS中,客观PM与主观PM (β=-0.18,P=.036) 有显著的关联.
- 基于时间的PM性能与主观的PM具体相关.
- 身体残疾,抑郁和疲劳也对主观的PM评级作出了重大贡献.
结论:
- 目标PM表现与PwMS中轻度损伤和症状的自我评估有关.
- PDQ-PM可以作为一种补充工具,用于识别MS中的PM困难.
- 这些发现有助于理解多发性硬化症的认知差异.
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