晚期或复发性肺癌患者的体力活动和预后以及与低体力活动相关的因素:一项回顾性观察性研究
Takuya Fukushima1, Utae Katsushima2, Naoya Ogushi3
1Faculty of Rehabilitation, Kansai Medical University, Hirakata, Osaka, Japan.
BMJ supportive & palliative care
|September 5, 2024
概括
低体力活动与晚期肺癌患者的生存率较差有关. 通过迷你营养评估简单表格 (MNA-SF) 评估的营养状况与身体活动水平有关.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 营养科学 营养科学
背景情况:
- 肺癌的预后受到各种因素的影响.
- 身体活动和营养状况是癌症患者结果的潜在调节者.
- 了解这些关系可以为支持性护理策略提供信息.
研究的目的:
- 检查晚期或复发性肺癌患者体育活动和预后之间的关联.
- 为了确定与该人口的体力活动水平相关的因素.
主要方法:
- 50名接受化疗的肺癌门诊患者的回顾性观察性研究.
- 评估体力活动 (国际体力活动问卷简单表) 和营养状况 (迷你营养评估简单表 [MNA-SF]).
- 统计分析包括日志等级测试,考克斯比例危险模型和后勤回归.
主要成果:
- 较低的体力活动与较差的生存率有显著的关联 (危险比率 [HR],4.35;p=0.029).
- 通过MNA-SF测量的营养状况是与低体力活动相关的重要因素 (异常比率[OR],0.71;p=0.038).
- 低体力活动的MNA-SF切线被确定为9.5点.
结论:
- 低体力活动可能成为肺癌的预后指标.
- 营养状况与这些患者的体力活动水平有关.
- 在临床实践中,建议定期进行MNA-SF评估和以营养为基础的身体活动干预措施.
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