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Updated: Jun 14, 2025

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
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口服生物可用性提高不太溶解的药物通过无形固体分散使用糖酸盐异酸盐

Eman M Mohamed1,2, Sathish Dharani1, Tahir Khuroo1

  • 1Irma Lerma Rangel School of Pharmacy, Texas A&M Health Science Center, Texas A&M University, 310 Reynolds Medical Sciences Building, College Station, Texas, 77843-1114, U.S.A.

AAPS PharmSciTech
|September 5, 2024
PubMed
概括

这项研究使用酸异酸盐 (SAIB) 开发了阿普雷皮坦的无形固体分散 (ASD),显示出可比的稳定性和生物可用性与基于HPMC的不溶性药物的配方相比.

关键词:
无形固体分散的无形固体分散有关药物的药剂.药物动力学 药物动力学稳定的稳定性 稳定的稳定性糖酸盐和糖酸盐是不同的.

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