在急性胰腺炎住院的ICU后患者肌肉恢复的量化:一项纵向单中心研究
Clarissa Hosse1, Nick L Beetz2,3, Uli Fehrenbach2
1Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany. clarissa.hosse@charite.de.
BMC anesthesiology
|September 5, 2024
概括
患有严重胰腺炎的重症患者经历了显著的肌肉损失. 虽然大多数人在出院后恢复了一些肌肉质量,但只有三分之一的人完全康复,这凸显了针对性康复的必要性.
科学领域:
- 密集护理医学 密集护理医学
- 关键的护理关键的护理
- 放射学 放射学是一门学科.
- 人工智能的人工智能
背景情况:
- 严重的急性胰腺炎 (AP) 在重症患者中导致显著的肌肉损耗,影响恢复.
- 现有的AP幸存者的研究侧重于胰腺功能,生活质量和成本,但缺乏全面的关于退院后肌肉质量变化的数据.
- 肌肉缩是影响严重疾病幸存者的结果的关键因素.
研究的目的:
- 为了量化重症监护室 (ICU) 患者在严重急性胰腺炎后出院后的肌肉质量恢复.
- 利用基于人工智能的自动细分工具来精确测量肌肉质量变化.
- 在严重的AP幸存者中确定肌肉恢复的模式和变化.
主要方法:
- 用人工智能工具对22名患者进行了肌肉细分.
- 在入院,出院和住院后的随访中测量了Psoas肌肉区域 (PMA).
- 包括T测试在内的统计分析被用来比较肌肉质量变化,并确定恢复预测因素.
主要成果:
- 患者在住院期间经历了大量的肌肉损失,平均psoas肌肉面积 (PMA) 减少了40.18%.
- 平均随访时间为438.73天后,81%的患者显示肌肉质量增加.
- 只有27%的患者实现了肌肉完全恢复到入院前的状态,大多数患者仍然存在显著的缺陷.
结论:
- 在严重的AP患者中,肌肉的恢复是高度可变的,少数人实现完全恢复.
- 人工智能支持的成像分析可以精确量化肌肉状况,并识别需要康复的患者.
- 了解肌肉缩动态对于改善预后和个性化患者护理至关重要.
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