相关实验视频

Updated: Jul 19, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

SEPT9:从胰腺癌到肺状细胞癌

Wenwen Wang¹, Xiaochen Zhang², Ping Gui³

¹Translational Medicine Research Center, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, 310006, Zhejiang, China.

|September 5, 2024

概括

一种关键蛋白质SEPT9,在许多癌症中表达高,与糟糕的结果有关. 向SEPT9对癌症查,预后和免疫治疗有前途,特别是在肺状细胞癌 (LUSC) 中.

科学领域:

在瘤学瘤学.
分子生物学分子生物学
遗传学遗传学是一个

背景情况:

SEPT9是一种关键的GTPase,参与细胞分裂.
以前的研究表明SEPT9在癌症中的作用,但缺乏全面的泛癌研究.

研究的目的:

系统地研究SEPT9在多种癌症类型的癌症查,预后和治疗中的作用.
为了验证SEPT9在肺状细胞癌 (LUSC) 的临床意义.

主要方法:

来自公共数据库的基因和蛋白质表达数据的全癌症分析.
使用LUSC患者样本和免疫组织化学的实验验验证.
分子对接以评估药物与蛋白质相互作用.

主要成果:

SEPT9在各种癌症中过度表达,与遗传变化和不良预后相关.
SEPT9促进瘤的进展,并影响瘤的免疫微环境,可能增强免疫疗法反应.
一个新的LUSC预后模型,包括SEPT9,改善了结果预测和建议治疗策略.

结论:

SEPT9是一种潜在的泛癌生物标志物,用于查和预后.
SEPT9在LUSC进展和免疫调节中发挥着重要作用.
开发的预后模型为LUSC治疗提供了价值,包括免疫疗法和化疗.

关键词:

在 SEPT9上,你会得到很多东西.药物治疗是药物治疗.免疫治疗是一种免疫疗法.在LUSC中使用LUSC.预测模型是一个预测模型.瘤的免疫微环境

更多相关视频

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Published on: January 19, 2019

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression

Published on: March 17, 2020

相关概念视频

Cancer

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.