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Updated: Jun 14, 2025

A Novel Feeder-free System for Mass Production of Murine Natural Killer Cells In Vitro
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A Novel Feeder-free System for Mass Production of Murine Natural Killer Cells In Vitro

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黑色素通过JAK3-STAT5信号通路增加T-bet表达来增强老年小鼠的NK细胞功能

Caiying Liang1, Rongrong Song1, Jieyu Zhang1

  • 1Laboratory Center of The Sixth affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, Guangdong, China.

Immunity & ageing : I & A
|September 5, 2024
PubMed
概括

黑色素增加自然杀手 (NK) 细胞数量和功能在老化小鼠通过促进增殖和激活. 这项研究澄清了JAK3/STAT5路径.

关键词:
衰老的衰老 衰老的衰老这就是JAK3-STAT5的原因.黑色素是什么 黑色素是什么 黑色素是什么功能 NK 功能 NK 的功能.在T-bet上下注.

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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