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Updated: Jun 14, 2025

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针对癌症向治疗的抗PD-L1免疫毒素的开发和表征

Ali Takhteh1,2, Mohammad Hosseininejad-Chafi1, Akbar Oghalaie1

  • 1Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.

Current pharmaceutical biotechnology
|September 6, 2024
PubMed
概括

一种新型的免疫毒素 (IT) 针对编程细胞死亡利干-1 (PD-L1) 已通过将抗PD-L1纳米体 (Nb) 与截断的甲状腺毒素 (DT) 融合而成功构建. 这种IT证明了强大的癌细胞细胞毒性,显示了癌症免疫治疗的前景.

关键词:
双菌毒素的使用方法在PD-L1中.抗PD-L1.1. 的情况.药物输送是药物输送的过程.免疫毒素是一种免疫毒素.纳米体是一个纳米体.针对性治疗的目标治疗.

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