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Updated: Jun 14, 2025

Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications
10:12

Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications

Published on: April 21, 2023

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通过DNA损伤介导的FTO下调促进CRPC进展,通过通过m6A依赖机制抑制FOXO3a

Lele Xu1, Yuting Chen1,2, Tao Wu3

  • 1Shenzhen Key Laboratory of Viral Oncology, The Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.

iScience
|September 6, 2024
PubMed
概括

脂肪质量和与肥胖相关的蛋白质 (FTO) 水平在前列腺癌中较低,促进瘤生长. 恢复FTO可以增强聚氨酸二酸聚合酶抑制剂 (PARPi) 治疗疗效,治疗割抵抗性前列腺癌.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学分子生物学分子生物学

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