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在接受维持血液透析的患者中,相角与肉症的关联:一项病例对照研究
Amirhesam Alirezaei1, Amirhossein Miladipour1, Navid Asgari1
1Clinical Research and Development Center, Shahid Modarres Educational Hospital, Division of Nephrology, Department of Internal Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
概括
麻症影响40%的血液透析患者,女性不成比例地受到影响. 诸如相角,身体组成和年龄等因素会影响脏病患者的肉症.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 肌肉生理学 肌肉生理学
背景情况:
- 由肌肉强度和质量下降所定义的肉类,在病患者中很普遍.
- 维持血液透析 (HD) 患者经常表现出肉症.
- 了解影响HD患者肉症的因素对于管理病并发症至关重要.
研究的目的:
- 为了调查在接受维护血液透析的患者中,萨科佩尼亚的患病率.
- 在这个患者群体中识别与肉类相关的因素.
主要方法:
- 一项涉及137名维持血液透析患者的病例控制研究.
- 数据收集包括通过生物电阻分析的患者人口统计学,身体组成和相角 (PhA).
- 根据诊断标准,患者被分为sarcopenia和non-sarcopenia组.
主要成果:
- 在维护性疾病患者中,肉类的患病率为40.14%.
- 女性 (76.36%) 比男性 (P < 0.001) 更常见的是肉类.
- 阶段角 (PhA) 在两组之间显著不同 (P < 0.006) 并与BMI,体细胞质量,基础代谢率,无脂肪质量,软瘦质量和矿物质正相关,而与年龄和骨肌肉指数相反相关.
结论:
- 在维护血液透析患者中,萨科佩尼亚是一个重大问题,与增加的死亡风险有关.
- 识别和治疗皮症对于改善病患者的健康状况至关重要.
- 诸如相角,身体组成和年龄等因素是这种人群中萨尔科佩尼亚的关键决定因素.
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