对于患有Modic I和II变化的慢性迪斯科原性腰部疼痛患者的阶段性护理治疗的有效性
Heidi Mylenbusch1, Michiel Schepers1, Elmar Kleinjan1
1Stichting Rugpoli Twente, Veluwe, Brabant, Randstad - Multidisciplinary Center for Spine and Musculoskeletal Disorders, the Netherlands.
Interventional pain medicine
|September 6, 2024
概括
这项研究表明,Modic变化 (MC) 的逐步护理治疗有效地减少了慢性腰部疼痛,并改善了超过一半的患者的功能. 抗炎方法是安全的,具有成本效益和可重复性的.
科学领域:
- 整形外科 整形外科 整形外科
- 疼痛管理 疼痛管理
- 炎症性疾病 炎症性疾病
背景情况:
- 模式变化 (MC) 与慢性腰部疼痛 (CLBP) 有关.
- 对MC相关的CLBP需要有效的治疗策略.
- 抗炎治疗提供了一个潜在的治疗途径.
研究的目的:
- 为了评估阶段性护理的有效性,对患有MODIC变化 (MC) I,I/II和II类型的患者进行抗炎治疗.
- 评估患者报告的疼痛和功能方面的结果.
- 为了确定处理模型的安全性和可重复性.
主要方法:
- 对332名患有CLBP和MC的患者进行了观察性临床研究.
- 阶段性护理治疗:NSAID,内类固醇注射 (ID) 和口服抗生素 (AB).
- 12个月的随访评估疼痛缓解 (≥50%) 和功能改善 (≥40% RMDQ/ODI).
主要成果:
- 53.6%的患者在1年内达到应答者标准.
- 单独使用NSAIDs可以改善63.8%的患者.
- 内类固醇注射改善了56.8%的患者;抗生素改善了38.7%.
结论:
- 对于MC的炎症性疼痛,分级护理模式是有效和安全的.
- 这种治疗方法在疼痛和功能方面产生了临床相关的改善.
- 该模型是可重复的,节省成本,并保证与RCT进行进一步的研究.
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