菲洛德斯乳腺瘤 - 在三级护理中心的经验
Atul Anand1, Chandan Kumar Jha2, Upasna Sinha3
1Department of General Surgery, All India Institute of Medical Sciences, Patna, Bihar 801507 India.
Indian journal of surgical oncology
|September 6, 2024
概括
乳房的Phyllodes瘤 (PTs),虽然通常是良性的,但可以局部复发. 这项研究发现,对于局部复发和边际阳性,无论乳腺保护手术或乳腺切除术对于大型PTs,结果都类似.
科学领域:
- 在瘤学瘤学.
- 乳房手术 乳房手术
- 病理学 病理学 病理学
背景情况:
- 乳腺瘤 (PTs) 是一种罕见的乳腺瘤,具有诊断和治疗方面的挑战.
- 尽管PT大多是良性的,但PT表现出局部复发的倾向,通常需要辅助疗法.
研究的目的:
- 确定PT患者的临床病理学特征和治疗结果.
- 评估外科手术对PT管理中的复发和边际状况的影响.
主要方法:
- 在2017年12月至2023年12月期间,对52名为PT手术治疗的妇女进行了回顾性分析.
- 数据收集包括人口,临床,放射 (BI-RADS),病理 (良性,边缘性,恶性) 和随访细节.
- 统计分析比较了乳房保护手术 (BCS) 和乳房切除手术之间的结果,重点关注边际阳性和局部复发.
主要成果:
- 患者的平均年龄为38.2岁,57.7%为绝经前.
- 核心针活检 (CNB) 是手术前的主要诊断工具 (65.4%).
- 宽局部切除 (WLE) 在63.5%和乳腺切除在36.5%中进行. 良性,边缘性和恶性PT分别为67.3%,15.4%和17.3%. 利率的积极性总体为34.6%. 在BCS患者中,瘤大小显著减少 (p < 0.001). 在WLE和乳腺切除术之间,局部复发率没有显著差异 (p = 0.400).
结论:
- 大型PT的外科结果,关于边缘阳性和局部复发,在乳腺保护手术和乳房切除术之间是可比的.
- 负病理边缘宽度大于1mm被认为是可以接受的.
- 具有正边缘的恶性PT与更高的复发率相关,而其他亚型的正边缘可能不会导致短期复发.
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