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传统中医药对格雷夫斯病的影响:一个网络元分析

Zhuoshi Yang¹, Na Zhao², Jinchuang Li¹

¹First School of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.

Frontiers in pharmacology

|September 6, 2024

概括

传统中医药有效治疗格雷夫氏病 (GD),改善结局和甲状腺激素水平. 特定的草药,如阴江颗粒和益康丸,在治疗效果和TSH水平方面表现出卓越的结果.

科学领域:

内分泌学在内分泌学.
药理学药理学是一个学科.
综合医学是一个整体的医学.

背景情况:

格雷夫斯病 (GD) 是一种常见的自身免疫性疾病,导致甲状腺功能障碍,目前治疗方法有限.
传统中医 (TCM) 提供了一个有前途的途径来管理GD的进展和开发新的治疗方法.

研究的目的:

进行网络元分析,比较格雷夫斯病的各种TCM.
评估TCM在临床结果和关键甲状腺功能标志物的有效性.

主要方法:

在多个数据库 (PubMed,Embase,Cochrane等) 进行了搜索. 对于随机对照试验 (RCT),最长期限为2023年12月.
包括35个RCT,包括2828名GD患者,使用R软件分析数据.
根据偏差风险评估所包含研究的质量.

主要成果:

一些中医药,包括Bailing Capsule和Jiakangling Capsule,表现出比西方医学更好的治疗效果.
普鲁内拉俗 (L.) 颗粒和Yikang药丸改善了TSH水平,而普鲁内拉俗 (L.) 颗粒,P. vulgaris (L.) 口服液和Yikang药丸降低了FT3和FT4水平.
口服液有效降低了TPOAb和TRAb水平,Yinjia颗粒显示出最好的整体治疗效果.

结论:

在改善临床结果和甲状腺激素水平方面,TCM是有效的格雷夫病患者.
特定的TCM如Yinjia颗粒,Yikang药丸,Prunella vulgaris (L.) 颗粒和P. vulgaris (L.) 口服液显示出对GD管理的不同方面有显著的好处.

关键词:

格雷夫斯的疾病.自由的甲状腺素是没有的.自由的三甲氨酸.网络元分析网络元分析甲状腺刺激激素激素是什么传统的中医药是传统的中医药.

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