初级甲状腺功能障碍症的身体组成:对疲劳和疲劳的潜在贡献者
Paul M Bunch1, Erik D Johansson1, Joseph Rigdon2
1Department of Radiology, Wake Forest University School of Medicine, Winston Salem, NC, USA.
The American surgeon
|September 6, 2024
概括
在一次性甲状腺功能障碍症 (PHPT) 中,下骨肌指数 (SMI) 与女性的软弱有关. 在PHPT患者中,身体组成的变化可能因性别而异.
科学领域:
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
- 身体组成分析 身体成分分析
背景情况:
- 原发性偏甲状腺症 (PHPT) 经常导致虚弱和疲劳.
- 在PHPT中这些症状的潜在机制仍然不清楚.
- 调查身体组成可能会揭示PHPT相关症状的洞察力.
研究的目的:
- 评估计算机断层扫描 (CT) 导出的肌肉和脂肪组织指标与PHPT患者的软弱/疲劳之间的关联.
- 为了确定身体组成指标是否与PHPT中的症状严重程度相关.
主要方法:
- 对53名PHPT患者的CT扫描进行了回顾性分析.
- 从L3脊椎水平CT图像计算骨肌肉指数 (SMI) 和内脏脂肪组织 (VAT) /皮下脂肪组织 (SAT) 的比例.
- 用已确定的性别特异性SMI值来定义的肉类;收集的人口和临床数据.
主要成果:
- 45%的患者报告了虚弱,81%的疲劳,58%的患者患有肉症.
- 较低的SMI与女性的手术前虚弱有显著的关联,但男性没有.
- 症状女性的VAT/SAT比率较高,而症状男性的比率较低,尽管在统计学上没有显著意义.
结论:
- 患有PHPT的女性手术前的虚弱显著与较低的SMI有关.
- 甲状腺激素对骨肌肉和内脏脂肪的影响可能会呈现出性别特异性的差异.
- 在副甲状腺切除术后没有观察到显著的身体组成变化.
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