北卡罗来纳大学癌症生存队列:合作生存研究的资源
Chelsea Anderson1, Jeannette T Bensen2,3, Emma H Allott4
1Center for Gastrointestinal Biology and Disease, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
概括
北卡罗来纳大学 (UNC) 癌症幸存者队列是一个宝贵的资源. 这项研究详细介绍了队列.
科学领域:
- 在瘤学瘤学.
- 癌症生存率研究 癌症生存率研究
- 临床数据整合技术
背景情况:
- 越来越多的美国癌症幸存者需要进行研究,以提高癌症后的结果和经验.
- 北卡罗来纳大学 (UNC) 癌症幸存者队列是一个医疗中心的资源.
- 这个队列整合了电子病历数据,患者报告的结果和生物标本.
研究的目的:
- 描述北卡罗来纳大学 (UNC) 癌症幸存者队列.
- 为癌症幸存者研究建立一个全面的资源.
- 通过收集各种数据类型和生物标本来促进未来的研究.
主要方法:
- 成年参与者 (18岁以上) 来自UNC瘤诊所 (2010年4月至2016年8月).
- 通过调查问卷收集的数据包括人口统计,病史,获得医疗保健,生活质量和症状.
- 医疗记录提供了癌症特征和临床数据;收集了血液和瘤组织样本.
主要成果:
- 该队列包括3,999名癌症幸存者,常见的癌症是乳腺癌,子宫癌,结肠直肠癌,前列腺癌以及头癌.
- 从76%的癌症幸存者中收集了生物样本 (血液).
- 另有1,299名没有癌症的参与者被录取,其中62%提供了生物样本.
结论:
- 联合国加州大学癌症幸存者队伍是促进癌症幸存者研究的独特和有价值的资源.
- 该队列通过数据链接和生物标本分析支持协作研究.
- 鼓励研究人员在未来的研究中利用这个资源.
更多相关视频
09:18Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
8.3K
07:44Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
Published on: November 28, 2019
7.5K
相关概念视频
01:20Comparing the Survival Analysis of Two or More Groups
712
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
712
01:21Cancer Survival Analysis
863
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
863