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对比131I和/或人造肝脏支持系统对肝功能衰竭和甲状腺功能过高的预后影响

Danzhou Fang¹, Shiying Li², Changgu Zhou³

¹Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Endocrine connections

|September 6, 2024

概括

放射性 (131I) 治疗,有或没有人工肝支持 (ALSS),有效地管理肝功能衰竭患者的甲状腺功能障碍. 结合131I和ALSS显示出最好的结果,改善肝功能和降低死亡率.

科学领域:

内分泌学在内分泌学.
肝病学肝病学是一种肝病学.
核医学是一种核医学.

背景情况:

甲状腺功能障碍会导致由于甲状腺激素代谢导致的肝衰竭.
格雷夫斯病是甲状腺功能障碍的常见原因之一.
肝功能对于甲状腺激素调节至关重要.

研究的目的:

评估放射性 (131I) 和/或人造肝支持系统 (ALSS) 在治疗与同时存在严重肝衰竭的甲状腺功能增强症的有效性.
为了比较131I治疗,联合131I和ALSS治疗以及单独治疗ALSS的结果.

主要方法:

74名患有严重肝衰竭和格雷夫斯病的患者的回顾性分析.
患者被分为三组:131I治疗 (A组),131I+ALSS治疗 (B组) 和单独治疗ALSS (C组).
评估的结果包括肝脏和甲状腺功能指数,疗效率和死亡率.

主要成果:

131I治疗 (A组和B组) 显著改善了甲状腺功能和肝功能.
B组 (131I + ALSS) 显示了最高的疗效率 (82.35%) 和最低的死亡率 (5.88%).
组C (单独ALSS) 的疗效最低 (60.87%) 和死亡率最高 (36%).

结论:

建议在严重肝功能衰竭的甲状腺功能过高症下给予Prompt 131I.
结合131I和ALSS治疗在管理这种复杂的疾病方面提供了卓越的结果.
131I治疗有助于通过解决甲状腺功能过高的不良影响来恢复肝功能.

关键词:

第131章一百三十一章人工肝脏支持系统的人工肝脏支持系统甲状腺功能过强症甲状腺功能过强症肝功能衰竭肝功能衰竭肝功能衰竭

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