扣押预测的自动化算法:系统审查和元分析
Ana Sofia Carmo1,2, Mariana Abreu3,4, Maria Fortuna Baptista5,6
1Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal. ana.sofia.carmo@tecnico.ulisboa.pt.
Journal of neurology
|September 6, 2024
概括
自动预测算法显示出有希望的表现,平均AUC为0.71. 本次审查强调了在开发患者特定的预测工具时需要标准化的方法.
科学领域:
- 神经学 神经学
- 生物医学工程 生物医学工程
- 数据科学数据科学数据科学
背景情况:
- 发作对患者的管理和生活质量构成重大挑战.
- 自动发作预测旨在预测发作,使主动干预成为可能.
- 现有的算法在方法和性能上有所不同,需要进行全面的审查.
研究的目的:
- 系统地审查和描述自动预测算法的方法和性能.
- 为当前的扣押预测技术建立一个基准.
- 确定缺口,并为未来的研发提出指导方针.
主要方法:
- 对2024年5月10日之前发表的研究进行系统性文献综述.
- 纳入标准:原始,针对患者的算法,用于预测人类发作,使用个人内周期事件分布和/或替代性前状态措施.
- 进行了两个元分析:一个是ROC曲线下的面积 (AUC),另一个是Brier技能得分 (BSS).
主要成果:
- 18项研究符合资格标准,包括43个独特的算法和来自419名患者的数据,其中有19442例报告的发作.
- 在符合条件的算法中,AUC的整体平均值为0.71,无论输入数据类型 (周期性事件,替代措施或组合) 如何,性能都相似.
- 总体平均屏障技能得分 (BSS) 为0.13,也显示了不同输入数据策略的一致性.
结论:
- 自动预测算法表现出一致的,中等水平的性能,以0.71.7的平均AUC表示.
- 研究人员发现,在研究设计和绩效评估方面,缺乏标准化.
- 建议提出指导方针,以促进标准化,并推进可靠的预测解决方案的开发.
更多相关视频
06:28Author Spotlight: Unraveling Seizure Dynamics and Novel Therapeutics for Status Epilepticus Using CMOS High-Density Microelectrode Array Systems
Published on: September 27, 2024
2.3K
09:16Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
25.6K
相关概念视频
01:13Seizures: Classification
309
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
309
01:24Arteries of the Lower Limbs
181
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
181