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Updated: Jun 14, 2025

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates
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通过JAK2/STAT3轴,TREM2损害糖解,以中断微质M1的极化和炎症

Chanyuan Liu1, Xueying Zhou2

  • 1Psychiatric Ward 1, Wuhan Wuchang Hospital, Wuhan, 430061, Hubei, China.

Cell biochemistry and biophysics
|September 6, 2024
PubMed
概括

在骨髓细胞2 (TREM2) 上表达的触发受体通过减少炎症和糖解提供了对脑缺血/再损伤 (IRI) 的保护. 在中风模型中,TREM2 禁用了 JAK2/STAT3 途径,促进了有益的 M2 巨细胞两极分化.

关键词:
葡萄糖溶解是什么? 葡萄糖溶解在JAK2/STAT3轴上在M1/M2极化中.微质细胞中的微质细胞在OGD/R中,在TREM2中,我们可以使用TREM2.

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