在阻塞性睡眠呼吸暂停的下器装置治疗 - - 一个结构化的治疗调整,考虑到下器装置的夜间变化
Greta Sophie Papenfuß1, Inke R König2, Christina Hagen3
1Department of Otorhinolaryngology, University of Lübeck, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Sleep & breathing = Schlaf & Atmung
|September 6, 2024
概括
部推进装置 (MAD) 通过减少夜间变化 (NNV) 有效地治疗阻塞性睡眠呼吸暂停 (OSA). 60%的突出设置显著改善了OSA的严重程度和嗜睡,这表明MAD即使在较高的NNV的情况下也适合使用.
科学领域:
- 睡眠医学 睡眠医学
- 牙科 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 部推进装置 (MAD) 是阻塞性睡眠呼吸暂停 (OSA) 的首要治疗方法.
- 特别推使用MAD治疗轻度至中度OSA,夜间变异性 (NNV) 较高.
研究的目的:
- 评估MAD对NNV的影响.
- 评估不同突起距离对NNV和患者相关结果 (PRO) 的影响.
主要方法:
- 在60%和80%突起的情况下使用MAD的患者的前性队列分析.
- 家庭睡眠测试评估了两个连续晚上的OSA严重程度 (呼吸暂停-呼吸暂停指数 - AHI).
- 与患者相关的结局包括爱普沃思睡眠度量 (ESS) 和睡眠问卷的功能结果 (FOSQ).
主要成果:
- 包括20名患有轻度至中度OSA (中位数AHI 18.3/h) 的患者.
- 60%的突出设置显著降低了AHI (11.2/h),并改善了ESS (8.0),与80%的设置不同.
- 没有发现NNV和ESS或FOSQ变化之间的相关性;更高的基线NNV与严重的OSA相关.
结论:
- OSA的改善与减少的NNV相关,两者都受到MAD突起的影响.
- 增加的NNV不应该排除患者从MAD治疗.
- PRO的变化与一般的OSA改进有关,而不是具体的NNV.
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