塑料暴露与中国老年人认知功能的关联
Yongbin Zhu1, Yueping Wu1, Liping Shi1
1Department of Epidemiology and Health Statistics, School of Public Health, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China.
Journal of Alzheimer's disease : JAD
|September 6, 2024
概括
增加塑料产品的暴露与老年人轻度认知障碍 (MCI) 的风险更高有关. 经常使用塑料餐具与这种风险增加特别相关.
科学领域:
- 环境健康 环境健康
- 老年学是一门学科.
- 神经科学是一个神经科学.
背景情况:
- 广泛接触塑料制品带来了社会挑战.
- 在老年人群中认知障碍的增长率需要对促成因素进行研究.
研究的目的:
- 调查中国老年人每日接触塑料产品和认知功能之间的关联.
- 探索剂量反应关系,并确定与认知衰退相关的特定塑料暴露模式.
主要方法:
- 利用了2023年宁夏老年心理健康队列 (4045名参与者,年龄60岁以上) 的数据.
- 使用迷你精神状态检查 (MMSE) 评估认知功能.
- 通过问卷计算塑料暴露分数 (PES),并采用后勤回归,受限立方线和隐性配置分析 (LPA).
主要成果:
- 在较高的塑料暴露分数 (PES) 和轻度认知障碍 (MCI) 风险增加之间发现了显著的关联.
- 证实了PES和MCI风险之间的剂量反应关系.
- 隐性资料分析发现了两种暴露模式,其中塑料用具使用与较高的MCI风险有关.
结论:
- 较高水平的塑料产品暴露与患MCI的风险有积极的相关性.
- 塑料餐具的使用成为老年人认知障碍的特定风险因素.
相关概念视频
01:30Cognitive Development During Adulthood
72
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
72
01:27Language and Cognition
338
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
338
01:26Alzheimer's Disease: Overview
454
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
454
01:26Aging
40
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
40