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Updated: Jun 14, 2025

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
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Published on: October 28, 2014

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MYC驱动mRNA伪化以减轻在癌症发育期间因增殖引起的细胞压力

Jane Ding1,2, Mohit Bansal1,2, Yuxia Cao1,2

  • 1Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.

Cancer research
|September 6, 2024
PubMed
概括

在癌症中,MYC瘤基因激活了伪尿素合成酶7 (PUS7),它通过通过ATF4.4促进氨基酸生产和应激反应来帮助细胞在压力中生存. 准PUS7可能治疗MYC驱动的癌症.

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