音节处理组织在人类上部状回路的离散子区域
Daniel R Cleary1,2, Youngbin Tchoe3, Andrew Bourhis3
1Department of Neurosurgery, University of California San Diego, La Jolla, California, United States of America.
PLoS biology
|September 6, 2024
概括
人类大脑中的语音处理可能以离散的1.7毫米模块发生. 后部上旋中的这些独特的处理模块显示了明确的边界和多样化的响应时间,表明了基本的组织原则.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 语音处理 语音处理
背景情况:
- 模块化组织是感官处理的一个关键原则.
- 它在人类关联皮层中的存在,特别是对于接受性语言,仍然在很大程度上是未知的.
- 了解这种组织对于破译复杂的认知功能至关重要.
研究的目的:
- 调查在语音接收处理过程中,人类后部上时环中模块化组织的存在和特征.
- 确定这些潜在模块的规模和边界.
- 探索这些模块的功能性质.
主要方法:
- 使用定制建造的高密度电极阵列 (1,024通道,200微米距) 在7名接受清醒切割的患者的皮质表面上.
- 记录神经对辅音母音音节和噪音声码控制器的反应.
- 分析了域大小,边界度和响应延迟的数据.
主要成果:
- 鉴定出大致为圆形的,直径约为1.7毫米的区域,位于后部上部周.
- 观察到相邻域之间的清晰界限,与柱状组织一致.
- 发现双模分布的音节 (252毫秒和386毫秒) 的峰值延迟,模块之间具有不同的时间过程和刺激选择性.
结论:
- 人类的感受性语言皮质可以组织成离散的处理模块.
- 这种模块化组织,在约1.7毫米的尺度上,可能是人类语音处理的基础.
- 这些发现为语言理解的神经架构提供了新的见解.
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