评估沿海水域和水产养殖系统中抗菌素耐药性风险的多方方法
Shin Giek Goh1, Luhua You1, Charmaine Ng1
1NUS Environmental Research Institute, National University of Singapore, 1 Create way, Create Tower, #15-02, Singapore 138602, Singapore.
Water research
|September 6, 2024
概括
抗菌素耐药性 (AMR) 是水产养殖中日益严重的威胁. 这项研究监测了热带沿海水产养殖中的AMR,发现了不同的模式并确定了影响其传播的因素,这对于风险管理至关重要.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 水产养殖科学 水产养殖科学
背景情况:
- 抗菌素耐药性 (AMR) 是一个重大的全球挑战,影响水产养殖和海洋生态系统.
- 了解沿海环境中的AMR动态对于可持续的水产养殖和公共卫生至关重要.
研究的目的:
- 研究热带水产养殖和海洋环境中抗生素耐药细菌 (ARB),抗生素耐药基因 (ARG),抗生素 (AB) 和化学化合物的流行和共发生情况.
- 识别导致AMR发展和传播的因素.
- 评估与水产养殖活动相关的抗菌耐药性风险.
主要方法:
- 全年监测开放养殖和循环水产养殖系统 (RAS) 和周边海洋区域.
- 对ARB,ARG,AB和化学污染物的分析.
- 阶层集群分析集成ARG,化学和环境数据.
- 使用MAR指数,CAMRI和RQ进行风险评估.
主要成果:
- 观察到明显的AMR模式,在RAS病例中具有更高的抗生素耐药性病毒流行率.
- 在RAS鱼样中大量存在的特定ARG (qepA,blaCTX-M,bacA).
- 环境和季节性变化显著影响了ARG和化学化合物分布.
- ARG与化学化合物之间的弱相关性表明,低度可能不会驱动抗性选择.
结论:
- 水产养殖系统,特别是RAS,有助于局部AMR热点.
- 环境因素和季节性在抗药性传播中发挥着关键作用.
- 综合性风险评估对于有效管理沿海水产养殖中的AMR至关重要.
关键词:
抗生素耐药性基因是抗生素耐药性的基因.抗生素耐药性细菌是一种抗生素耐药性的细菌.抗生素 抗生素是一种抗生素.抗微生物耐药性 抗微生物耐药性水产养殖是水产养殖的一种方式.开放子养殖是一种开放子养殖.再循环水产养殖系统的水产养殖系统.风险 风险 风险 风险 风险更多相关视频
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