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Updated: Jun 14, 2025

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
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Published on: November 8, 2018

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临床前毒性研究支持2DG用于治疗状态

Thomas P Sutula1, Nathan B Fountain2

  • 1Department of Neurology, University of Wisconsin, Madison WI, USA; Hexokine Therapeutics, Inc. Madison WI, USA.

Epilepsy & behavior : E&B
|September 6, 2024
PubMed
概括

2-deoxy-D-glucose (2DG) 显示出作为抗发作药物的前景. 临床前毒理学研究表明,静脉注射2DG可能安全用于急性治疗状态和急性重复性发作.

关键词:
2 - 脱氧 - D - 葡萄糖2 - 脱氧 - D - 葡萄糖是一种病.葡萄糖溶解抑制的抑制作用代谢过程中的代谢.

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Depolarizing Blockers: Pharmocokinetics01:19

Depolarizing Blockers: Pharmocokinetics

Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
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