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使用HR-CS-GFMAS通过GaF检测进行PFAS分析的优化方法

Fabian Simon¹, Marcus von der Au¹, Lennart Gehrenkemper¹

¹Federal Institute for Materials Research and Testing, Division 1.1 - Inorganic Trace Analysis, Richard-Willstätter-Straße 11, 12489, Berlin, Germany.

|September 6, 2024

概括

优化HR-CS-GFMAS方法用于对基和多基基物质 (PFAS) 的分析,提高了准确性. 修饰剂干燥预处理提高了对挥发性PFAS的敏感性,减少了可提取有机测量的错误.

科学领域:

环境化学环境化学
分析化学分析化学

背景情况:

使用可提取有机 (EOF) 和高分辨率连续源石墨炉分子吸收光谱学 (HR-CS-GFMAS) 进行透和多基基物质 (PFAS) 分析,可提供高灵敏度和选择性.
目前的HR-CS-GFMAS方法在干燥和加热过程中遭受挥发性PFAS损失,导致不准确的歧视和EOF确定精度降低.

研究的目的:

优化HR-CS-GFMAS方法,以实现更准确的PFAS分析.
提高各种PFAS的反应因子的灵敏度并减少其变异性.
为了解决现有的现实PFAS污染评估方法的局限性.

主要方法:

系统地确定各种PFAS的反应因子.
修饰剂干燥预处理步骤的实施.
用优化的干燥和加热协议对样品溶液进行连续注射.
调查水样中的矩阵效应,包括化物干扰.

主要成果:

优化显著提高了对挥发性PFAS的敏感性,特别是在干燥过程中添加 (Mg) 修饰剂.
反应因子的相对标准偏差从55%降至27%.
的仪器检测极限 (LOD) 和量化极限 (LOQ) 分别为1.71微克/升和5.13微克/升.
观察到特定物质的矩阵效应, perfluorooctanoic acid (PFOA) 在高化物度下显示信号抑制.

结论:

优化的HR-CS-GFMAS方法提供了更准确的有机和参数分析.
修饰器辅助干燥对于提高可挥发性PFAS的检测至关重要.
有效的样本制备以去除化物等干扰物质是可靠的PFAS量化所必需的.

关键词:

可以提取的有机 (EOF)化物化物化物高分辨率连续源-石墨炉分子吸收光谱学 (HRCSGFMAS)方法优化方法优化 -和多基基物质 (PFAS) 的使用.响应因子响应因子

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