呼吸不全对有呼吸道症状但没有确定的诊断的成年人的影响
Jared Bierbrier1, Emily Gerstein1, George A Whitmore2
1The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
Chest
|September 6, 2024
概括
患有未诊断的呼吸道症状的成年人经历了呼吸不全的重大影响,特别是那些保持比例受损螺旋计 (PRISm) 的成年人. 这种呼吸困难会影响医疗保健的使用,生活质量和工作生产力.
科学领域:
- 肺部医学 肺部医学
- 呼吸系统健康 呼吸系统健康
- 临床研究 临床研究
背景情况:
- 研究呼吸不全,风险因素以及未被诊断的呼吸系统症状的成年人对健康结果的影响.
- 评估与呼吸障碍相关的医疗保健利用,生活质量和工作生产力.
研究的目的:
- 为了确定呼吸障碍对成年人的影响,这些成年人呈现出未被诊断的呼吸道症状.
- 为了确定这个人群中呼吸障碍的危险因素和后果.
主要方法:
- 基于人口的研究,对2857名患有呼吸道症状的成年人进行了研究,这些人来自加拿大17个中心.
- 螺旋计 (支气管扩展前和后) 用于诊断COPD,喘或保存比值受损螺旋计 (PRISm).
- 使用经过验证的调查问卷评估呼吸障碍的影响;与年龄相匹配的对照组相比.
主要成果:
- 患有PRISm的个体报告了最具影响力的呼吸障碍 (平均得分63.0),其次是未被诊断的喘 (56.6) 和COPD (57.5),所有这些都明显高于对照组 (13.8).
- 患者的因素 (年龄,性别,BMI,吸烟,并发症) 解释了20.6%的呼吸障碍变化;疾病分类和肺功能分别解释了额外的12.4%和1.7%.
- 较大的呼吸障碍影响与医疗保健利用率增加,生活质量降低以及调整人口统计因素后工作生产率降低相关.
结论:
- 保留比率受损螺旋计 (PRISm) 与未诊断的呼吸道症状的成年人呼吸障碍的影响最大.
- 呼吸障碍严重负担医疗保健系统,并对患者的生活质量和工作生产力产生负面影响.
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