在2006年至2023年期间,澳大利亚的酒精药理疗发行趋势
Ebony Quintrell1,2, Amy Page3, Caitlin Wyrwoll4,5
1School of Population and Global Health, University of Western Australia, Nedlands 6009, Western Australia, Australia.
Alcohol and alcoholism (Oxford, Oxfordshire)
|September 6, 2024
概括
自2006年以来,澳大利亚用于治疗酒精使用障碍的纳尔特雷分发量显著增加,而阿卡姆普罗沙特分发量保持稳定. 尽管这种增长,酒精药物治疗的使用总体上仍然很低.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 酒精使用障碍 (AUD) 是一个重要的公共卫生问题.
- 药物治疗,如阿坎普罗沙特和纳尔特雷是AUD的可用的治疗方法.
- 了解处方模式对于评估治疗可访问性和吸收性至关重要.
研究的目的:
- 调查澳大利亚的阿坎普罗沙特和纳尔特雷的配药模式.
- 分析从2006年到2023年使用酒精药疗的趋势.
- 为了比较治疗时段的长度和在阿卡姆普罗沙特和纳尔特雷之间切换行为.
主要方法:
- 使用了由澳大利亚制药福利计划 (PBS) 补贴的药物的10%代表样本.
- 在2006年1月至2023年12月期间,已识别的个人分发了纳尔德或阿坎普罗沙特.
- 检查了同时发行药物,药物切换,治疗情节的长度,流行率和发病率.
主要成果:
- 分析了22,745名个人和117,548份处方药.
- 纳尔特雷克森的发放量大幅增加,翻了一番以上,而阿卡姆普罗萨特的发放量显示出最小的变化.
- 酒精药疗达到每10万个人的1354,其中2.9%的AUD患者接受治疗.
- 35-54岁的男性是最常见的人口统计学群体;从阿坎普酸转换为纳尔德更为频繁.
- 较长的治疗期 (≥3个月) 更常见于纳尔特雷,但整体坚持是低的 (5.1%).
结论:
- 在澳大利亚 (2006-2023年),纳尔特雷的开放量显著增加,与稳定的阿卡姆普罗沙特开放量形成鲜明对比.
- 尽管纳尔特雷克森的使用增加,酒精药物治疗的整体利用率相对于AUD的流行率仍然很低.
- 需要进一步努力,以改善澳大利亚AUD的药物治疗方法的获取和遵守.
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