较新的测试方式对于培养负性内心炎的准确诊断有什么用处
Lauren N Hirth1, Alexis Holman2, Jake Levine2
1Medical School, University of Michigan Medical School, Ann Arbor, Michigan, USA lnhirth@umich.edu.
BMJ case reports
|September 6, 2024
概括
一项新的无细胞DNA测试确定了Streptococcus pasteurianus,将内心炎与老年患者的复发性结肠癌联系起来. 这个案例突出显示了测试.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 分子诊断学 分子诊断学
背景情况:
- 患有多种并发症的老年患者,包括充血性心力衰竭,心房失常,心交门疾病和先前的结肠癌.
- 在炼时出现严重的呼吸障碍,导致成像显示了假肢关节和永久起器的植被.
- 最初的血液培养结果呈阴性,需要先进的诊断方法.
研究的目的:
- 报告卡里乌斯无细胞DNA测试在诊断内心炎复杂病例中的临床应用.
- 调查内心炎的病因因素及其与潜在恶性瘤的潜在关联.
- 为了证明无细胞DNA测试在识别常规血液培养遗漏的病原体方面的实用性.
主要方法:
- 一位80多岁的妇女接受了严重呼吸障碍的评估.
- 心脏成像揭示了假肢心肌和永久起器上的植被.
- 进行了无卡里乌斯细胞DNA测试,检测了1000多种病原体,灵敏度为87-93%.
- 由于Streptococcus bovis亚种pasteurianus的阳性结果,进行了腹部成像和内镜活检.
主要成果:
- 卡里乌斯试验确定了Streptococcus bovis的亚种pasteurianus.
- 随后的调查证实了复发的结肠恶性瘤.
- 患者在心脏干预之前成功进行了右结肠切除.
结论:
- 无细胞DNA卡里乌斯测试成功诊断出S. 帕斯图里亚纳斯 内心炎.内心炎.
- 这种诊断有助于及时检测复发性结肠癌.
- 这一案例强调了无细胞DNA测试在识别传染病原体和相关恶性瘤方面的临床实用性.
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