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胃肠道癌症的流行病学:2021年全球疾病负担研究的系统分析
Pojsakorn Danpanichkul1, Kanokphong Suparan2, Primrose Tothanarungroj3
1Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA pojsakorndan@gmail.com dr.karn.wi@gmail.com.
Gut
|September 6, 2024
概括
胃肠道癌症在2021年造成526万新病例和370万死亡. 虽然一些癌症的发病率有所下降,但结肠直肠,胰腺和肝癌的发病率正在上升,需要进行公共卫生干预.
科学领域:
- 全球健康 全球健康
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 胃肠道癌症占全球癌症死亡率的近三分之一.
- 这些癌症的全面全球负担需要彻底调查.
研究的目的:
- 评估胃肠道癌症的全球,区域和国家负担.
- 分析不同地理和社会经济因素的发病率和死亡率的趋势.
主要方法:
- 利用了来自2021年全球疾病负担数据库的食道,胃,结肠直肠,肝脏,胰腺和胆道癌的数据.
- 根据年龄标准化发病率 (ASIR) 和年龄标准化死亡率 (ASDR) 的计算,按性别,地区和社会人口统计指数 (SDI) 分层.
主要成果:
- 在2021年,胃肠道癌导致526万新病例和370万死亡.
- 结肠直肠癌的负担最高,其次是胃癌,食道癌,胰腺癌,肝癌和胆道癌.
- 结直肠,胰腺和肝癌的发病率 (由于代谢功能障碍相关的脂肪性肝病和与酒精有关的肝病) 从2000年到2021年显示出不断增加的趋势.
结论:
- 尽管食道癌,胃癌和胆道癌率有所下降,但结肠直肠癌,胰腺癌和肝癌的发病率正在上升.
- 专注于减少酒精消费,乙型肝炎免疫和管理代谢疾病的公共政策对于控制胃肠道癌症至关重要.
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