Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Microtubules in Cell Motility01:24

Microtubules in Cell Motility

3.2K
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
3.2K
Microtubules01:18

Microtubules

7.3K
Microtubules are the thickest cytoskeletal filaments with a diameter of 25 nm. In prokaryotic organisms, microtubules are commonly found in locomotory appendages like cilia and flagella. In eukaryotic cells, microtubules form specialized extensions for moving fluid over the surface, like those found in cells lining the intestine.
Microtubules have two structurally similar globular protein subunits: α and β tubulins. In the cytosol, the α and β tubulins form a heterodimer....
7.3K
Assembly of Complex Microtubule Structures01:32

Assembly of Complex Microtubule Structures

1.8K
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
1.8K
Microtubules in Signaling01:22

Microtubules in Signaling

1.7K
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like structures are present, generally one per cell. These are non-motile cilia in a 9+0 microtubules arrangement, where the central pair of microtubules are absent. The primary cilia arise from the basal body embedded in the cell membrane. Intraflagellar transport (IFT) carries requisite proteins from the cytoplasm to the cilium because the primary...
1.7K
Contact-dependent Signaling01:19

Contact-dependent Signaling

44.5K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
44.5K
Role of Microtubules in Cell Wall Deposition01:02

Role of Microtubules in Cell Wall Deposition

2.4K
Microtubules are small hollow tubes in eukaryotic cells. The cell wall microtubules are polymerized dimers of two globular proteins, α-tubulin and β-tubulin, two globular proteins. With a diameter of about 25 nm, microtubules are the widest components of the cytoskeleton. They help the cell resist compression and provide a track along which vesicles move through the cell or pull replicated chromosomes to opposite ends of a dividing cell. Microtubules go through quick cycles of...
2.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Clinical translation of TLR agonist-modified silicified cancer cell therapy supported by humanized mouse models.

Molecular therapy. Oncology·2025
Same author

Rational design of immunogenic nanoparticles as a platform to reduce ovarian tumor burden in mice.

International journal of pharmaceutics·2025
Same author

Rational Design of Immunogenic Nanoparticles as a Platform for Enhanced Ovarian Cancer Immunotherapy in Mice.

bioRxiv : the preprint server for biology·2025
Same author

Regional immune mechanisms enhance efficacy of an autologous cellular cancer vaccine with intraperitoneal administration.

Oncoimmunology·2024
Same author

Correction: Multivalent Presentation of MPL by Porous Silicon Microparticles Favors T Helper 1 Polarization Enhancing the Anti-Tumor Efficacy of Doxorubicin Nanoliposomes.

PloS one·2024
Same author

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer.

Advanced healthcare materials·2024

相关实验视频

Updated: Jun 14, 2025

Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy
07:20

Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy

Published on: February 18, 2022

2.5K

通过微管状高速公路进行细胞间通信.

Lorél Y Medina1, Rita E Serda2

  • 1Internal Medicine, University of New Mexico Health Science Center, Albuquerque, NM, USA.

Results and problems in cell differentiation
|September 6, 2024
PubMed
概括

道纳米管 (TNTs) 是细胞连接,可以在细胞之间传输材料. 这些结构通过共享必需成分和去除有害物质来促进细胞通信和生存.

科学领域:

  • 细胞生物学 细胞生物学
  • 分子生物学分子生物学

背景情况:

  • 道纳米管 (TNTs) 是细胞间的连接,促进物质交换.
  • TNTs是膜包裹的延伸,具有不同的直径和长度的活性细胞骨.
  • 较厚的TNT具有用于双向货物运输的微管网.

研究的目的:

  • 阐明道纳米管的结构和功能特性.
  • 了解TNTs在细胞间通信和细胞生存中的作用.
  • 调查TNT中货物运输的机制.

主要方法:

  • 显微镜技术可用于可视化TNT及其组件.
  • 生物化学测定用于识别与货物运输有关的蛋白质.
  • 细胞测试以评估TNTs在物质交换中的功能作用.

主要成果:

  • TNTs可以延伸超过300微米,并容纳大型货物.
  • 动氨酸细胞骨对于TNT形成至关重要.
  • 运动蛋白质,如丁氨酸和髓氨酸,通过TNT促进蛋白质,线粒体和纳米颗粒的双向运输.

结论:

  • 跨细胞突触是细胞合作和弹性必不可少的动态结构.
关键词:
癌细胞是癌细胞的一个组成部分.刚果座是一架高架车.巨细胞是一个巨细胞.这些微管是微管子.纳米颗粒 纳米颗粒扫描电子显微镜扫描电子显微镜挖掘纳米管的道

更多相关视频

Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence TIRF Microscopy
08:44

Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence TIRF Microscopy

Published on: July 20, 2022

3.4K
Self-Assembly of Microtubule Tactoids
08:49

Self-Assembly of Microtubule Tactoids

Published on: June 23, 2022

3.8K

相关实验视频

Last Updated: Jun 14, 2025

Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy
07:20

Simultaneous Visualization of the Dynamics of Crosslinked and Single Microtubules In Vitro by TIRF Microscopy

Published on: February 18, 2022

2.5K
Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence TIRF Microscopy
08:44

Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence TIRF Microscopy

Published on: July 20, 2022

3.4K
Self-Assembly of Microtubule Tactoids
08:49

Self-Assembly of Microtubule Tactoids

Published on: June 23, 2022

3.8K
  • 它们使细胞能够作为一个协调的单元发挥作用.
  • 通过允许重要物质的转移和毒素的去除,TNTs有助于细胞的寿命.