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Updated: May 6, 2026

A Free-breathing fMRI Method to Study Human Olfactory Function

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

嗅觉训练足以使用四种气味剂:试点研究

Nicole Power Guerra¹, Emely Kruschwitz², Dietmar Krautwurst³

¹Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Smell & Taste Clinic, Technische Universität Dresden, 01307, Dresden, Germany. Nicole.powerguerra@ukdd.de.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|September 6, 2024

概括

嗅觉训练 (OT) 使用4或7种气味3个月改善了嗅觉功能,同样在患有嗅觉障碍的患者中. 气味的数量没有显著影响嗅觉训练结果.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
神经科学是一个神经科学.
感官科学感官科学

背景情况:

嗅觉训练 (OT) 是对嗅觉障碍的常见治疗方法,但最佳方案仍在争论中.
这项研究比较了3个月的OT,使用了4个和7个香水项目.

研究的目的:

为了比较4项与7项嗅觉训练在3个月的有效性.
评估OT对嗅觉功能,嗅觉值和相关症状的影响.

主要方法:

40名嗅觉功能障碍患者和60名对照患者接受了4项或7项OT (或对照组没有OT).
评估包括n-butanol的TDI得分,特定的气味值,幻觉/透视,认知功能和主观评分.
在3个月的干预期之前和之后进行了测量.

主要成果:

嗅觉训练 (OT) 显著改善了患者的TDI得分,无论使用4项还是7项.
从临床上显著的TDI得分增加5.5个点与降低质和改善主观嗅觉功能的评级相关.
在4项和7项组之间,OT结果是可比的.

结论:

用4种或7种气味进行3个月的嗅觉训练 (OT) 会产生类似的嗅觉功能的改善.
在OT中的香味物品数量可能不是治疗成功的关键因素,尽管样本大小值得考虑.

关键词:

与COVID-19相关的气味损失在MOCA测试中,我们进行了MOCA测试.嗅觉功能障碍嗅觉功能障碍嗅觉培训嗅觉培训嗅觉培训七种气味嗅觉训练嗅觉训练

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