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Updated: Jun 14, 2025

Derivation, Expansion, Cryopreservation and Characterization of Brain Microvascular Endothelial Cells from Human Induced Pluripotent Stem Cells
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布罗德曼区域46中的基因表达变化在精神分裂症和情绪障碍中区分表皮生长因子和免疫系统相互作用

Tharini Ketharanathan1,2,3, Avril Pereira4,5, Suresh Sundram6,7

  • 1The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC 3052, Australia. tharini.ketharanathan@unimelb.edu.au.

Schizophrenia (Heidelberg, Germany)
|September 6, 2024
PubMed
概括

早期的生活压力可能通过破坏免疫和表皮生长因子 (EGF) 信号通路,特别是在背侧前额皮质 (DLPFC) 中,改变精神分裂症患者的大脑发育. 这些干扰可能会增加精神分裂症风险倾向.

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Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
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