婴儿和没有的过度哭泣的早期生命风险因素
Karen M Switkowski1, Emily Oken2,3, Elisabeth M Simonin4
1Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA. karen_switkowski@hphci.harvard.edu.
Pediatric research
|September 6, 2024
概括
婴儿结肠,由腹部不适来定义,与过度哭泣不同. 多种风险因素增加了风险,这表明这种常见的婴儿问题有多因素的原因.
科学领域:
- 儿科 儿科 儿科
- 新生儿健康 新生儿健康
- 婴儿发育 婴儿发育
背景情况:
- 婴儿结肠的定义通常集中在哭泣上,可能会忽视胃肠道的痛苦.
- 不同的病因可能是过度哭泣与结肠的基础.
研究的目的:
- 为了在表型上区分结肠 (腹部不适) 和过度哭泣.
- 为了确定与婴儿和过度哭泣相关的危险因素.
主要方法:
- 6个月的母亲报告将婴儿分为未受影响的,仅过度哭泣的或的群体.
- 多项逻辑回归分析了过度哭泣和的风险因素.
- 后勤回归研究了风险因素数量与结肠之间的关联.
主要成果:
- 在1403名婴儿中,有25%患有;有10%过度哭泣.
- 结肠的危险因素包括非西班牙裔白人种族,低出生体重,长子身份,孕产妇的亚托皮,产后抑郁症和产前恶心.
- 过早分娩使结肠风险增加了一倍;第一胎,低出生体重和过早分娩预测过度哭泣.
- 患有四个或更多危险因素的婴儿患的几率高3.9倍.
结论:
- 带明显的腹部不适是表型上不同于过度哭泣.
- 多种风险因素导致结肠,支持多因素的病因.
- 仅仅基于哭泣的结肠的定义可能错过了关键的预测因素和危险因素.
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