面具的副作用与长期CPAP中的性别有关:来自InterfaceVent实践研究的结果
Celia Vidal1,2, Fanny Bertelli2, Jean-Pierre Mallet2,3,4
1IDESP, INSERM, PreMEdical INRIA, CHU Montpellier, Montpellier University, Montpellier, France.
Respiratory research
|September 6, 2024
概括
在长期CPAP治疗期间,女性经历更多与口罩相关的副作用,影响治疗坚持. 口腔干燥,而不是口罩的设计,显著影响了男女CPAP的使用情况.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 医疗器械研究 医疗器械研究
背景情况:
- 对女性睡眠呼吸暂停的理解有所发展,突出了其病理生理学,诊断和治疗方面的性别特异性差异.
- 之前没有实践研究研究了长期持续正气道压力 (CPAP) 治疗期间面具相关副作用 (MRSEs) 的性别差异.
研究的目的:
- 在现实生活环境中调查性别对患者报告的MRSE患病率的影响.
- 评估MRSEs如何影响CPAP的使用和坚持,考虑到性别差异.
主要方法:
- 在CPAP上接受至少3个月的呼吸暂停的成年患者中进行了前性,现实生活,横截面研究 (InterfaceVent-CPAP).
- 使用视觉模拟尺度 (VAS) 评估的MRSEs;CPAP不坚持定义为<4小时/天使用.
- 分析包括1484名患者 (27.8%为女性),不受限制地使用口罩.
主要成果:
- 患者报告的口罩损伤 (VAS ≥5) 在女性 (9.6%) 比男性 (5.3%) 更为普遍.
- 妇女报告说,使用鼻枕罩的口腔干燥VAS得分更高;男性报告说,使用口腔鼻膜的鼻水VAS得分更高.
- 口腔干燥独立地与CPAP使用量减少和两性不坚持增加有关.
结论:
- 在长期CPAP治疗期间,患者报告的MRSEs存在显著的性别差异.
- 未来的面具设计,特别是针对女性的面具设计,应该考虑这些性别特异性的副作用.
- 只有与口罩设计无关的口腔干燥会显著影响CPAP的使用和坚持.
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