波克斯病毒感染的神经影响:发病,神经缩和临床表现
Mohammed Alissa1, Khalid J Alzahrani2, Meshari A Alsuwat2
1Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Reviews in medical virology
|September 7, 2024
概括
包括小 Variola 病毒 (VARV) 在内的 Pox 病毒可以侵入中枢神经系统 (CNS). 这篇评论详细介绍了poxvirus神经断性,重点关注这些DNA病毒是如何导致中枢神经系统疾病,如脑炎.
科学领域:
- 病毒学 病毒学
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
背景情况:
- 普克斯病毒科 (Poxviridae) 是一个大型的双链DNA病毒家族.
- 从历史上看,病毒 (VARV) 导致了天花,一种严重的疾病.
- 麻疹病毒具有复杂的复制周期和庞大的基因组.
研究的目的:
- 审查当前关于牛病毒神经变的知识.
- 探索中枢神经系统 (中枢神经系统) 感染中毒病毒的机制.
- 突出临床表现和中枢神经系统的免疫介导损伤.
主要方法:
- 关于牛病毒神经化研究的文献综述.
- 综合病毒进入中枢神经系统的数据.
- 免疫反应和神经病变发生的分析.
主要成果:
- 波克斯病毒表现出显著的神经变潜力.
- 机制包括直接的病毒入侵和免疫媒介病理.
- 临床结局包括脑炎和骨髓炎.
结论:
- 脊髓灰质炎病毒感染存在神经系统并发症的风险.
- 了解神经化对于管理病毒相关的中枢神经系统疾病至关重要.
- 需要进一步研究预防和治疗策略.
相关概念视频
Disorders of the Nervous Tissue
1.1K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.1K
Parkinson's Disease: Overview
499
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
499
Postsynaptic Potential (PSP)
2.4K
Postsynaptic potential (PSP) refers to a change in the electrical potential of a neuron when neurotransmitters released by presynaptic neurons bind to postsynaptic receptors. This potential can either be excitatory, leading to depolarization and ultimately action potential generation, or inhibitory, leading to hyperpolarization and suppression of the postsynaptic neuron.
There are two types of receptors: ionotropic and metabotropic.
The ionotropic receptor is the membrane protein that has an...
There are two types of receptors: ionotropic and metabotropic.
The ionotropic receptor is the membrane protein that has an...
2.4K
Excitatory and Inhibitory Effects of Neurotransmitters
9.9K
When an action potential reaches the presynaptic axon terminal, it releases neurotransmitters from the neuron into the synaptic cleft at a chemical synapse. The released neurotransmitter can be excitatory or inhibitory. The critical criteria commonly used to determine whether a molecule is a neurotransmitter at a chemical synapse are the molecule's presence in the presynaptic neuron. Second, its release is in response to strong presynaptic depolarization. And lastly, the presence of...
9.9K


