使用专用设备进行过导管中枢替换后的结果,在患有中枢年结的患者中使用专用设备
Augustin Coisne1, Sebastian Ludwig2, Andrea Scotti3
1University Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France; Cardiovascular Research Foundation, New York, New York, USA.
JACC. Cardiovascular interventions
|September 7, 2024
概括
在中度至重度的中度环状化 (MAC) 患者中,通过管进行中枢置换 (TMVR) 显示出较高的并发症率,但与轻度MAC相比,存活率和功能结果相似. 在这一群体中,需要对专用TMVR设备进行进一步的研究.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 伴有显著的 mitra annular calcification (MAC) 的 mitra 反 (MR) 是一个复杂的临床挑战,治疗选择有限.
- 透导管 mitra 置换 (TMVR) 是一种新兴的治疗方法,用于严重的 MR.
研究的目的:
- 评估TMVR在中度至重度MAC患者的可行性和结果.
- 为了比较没有/轻度MAC和中度/重度MAC的患者之间的TMVR结果.
主要方法:
- 从CHOICE-MI注册表中分析了连续接受TMVR的患者.
- 根据CT数据将患者分为没有/轻度MAC和中度/重度MAC的分层.
- 技术成功,并发症率和临床结果在1年和2年后续的比较.
主要成果:
- 患有中度至重度MAC的患者在TMVR后出现更高的出血并发症和功能衰竭率.
- 在MAC组之间,技术成功率和MR消除率相似.
- 在2年的随访期间,所有原因死亡率,心血管死亡率或心力衰竭住院治疗没有显著差异.
结论:
- 在中度至重度的MAC患者中,TMVR是可行的,但与程序并发症的增加有关.
- 在TMVR后的生存和功能恢复在MAC严重程度组之间是可比的.
- 专用TMVR设备在中度至重度MAC中的作用需要进一步调查.
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